Malpractice Season 2: ITV Unveils First Images and New Star-Studded Cast for Gripping Medical Thriller

Season Two of Malpractice: ITV’s Medical Thriller Gets a Fresh Injection

If you’re into edge-of-your-seat dramas with a real-world bite, here’s something to look forward to. ITV just dropped the first look at the second season of its critically acclaimed medical thriller Malpractice, and we’ve got plenty to talk about. Based on the buzz alone, it’s shaping up to be even more intense than its breakout first season.

The show, penned by former NHS doctor Grace Ofori-Attah, isn’t your run-of-the-mill medical drama. Instead, it’s an anthology series that digs deep into the world of hospital investigations and blurred ethical lines. What sets Malpractice apart? It doesn’t just focus on what happens in the operating room, but why things can go so disastrously wrong—in a system that’s supposed to save lives. The script comes straight from someone who’s seen the pressure and high stakes up close.

New Faces, New Dilemmas: Meet the Cast and Story

Returning to the chaotic world of medical investigations are Helen Behan as Dr. Norma Callahan and Jordan Kouamé as Dr. George Adjei. If you remember them leading last season’s Medical Investigation Unit (MIU) with calm resolve and just the right hint of obsession, get ready—they’re back to tackle a whole new hospital scandal. The MIU is once again front and center, assigned to pick apart the latest accusation of malpractice thrown at a medical professional, with all the indirect pressure and grey areas you’d expect in real life.

The new cast lineup is star-studded. Tom Hughes, who you might know from Victoria or The English, steps in as Dr. James Ford. Selin Hizli, fresh off Grantchester and Am I Being Unreasonable?, plays Obstetrics Registrar Dr. Sophia Hernandez, bringing yet another layer to the series’ handling of complicated, personal hospital cases. Zoë Telford, a familiar face from Silent Witness and Sherlock, takes on the role of Consultant Psychiatrist Dr. Kate McAllister. Rounding out the support are Hannah McClean, Seraphina Beh, and Ace Bhatti—names you’ll recognize if you’ve been tuning in to British TV drama lately.

Because it’s an anthology, you don’t need to binge-watch the last series to jump in. Each season digs into a different case, picking apart not just who’s at fault, but how institutional pressures, personal grudges, or honest mistakes can spiral out of control. Season two promises a fresh dilemma for the MIU—a new suspect, tangled relationships, and the ever-present question: how do you tell medical error from genuine misconduct?

Produced by World Productions—the same folks behind Line of Duty—the series doesn’t shy away from real medical debates. It blends gripping drama with authentic glimpses into the lives of doctors under pressure. Timing-wise, ITV has nailed its release: the new season premieres on ITV1 and ITVX starting Sunday, May 4, 2025. You won’t have to wait long between episodes, either; they’ll be dropping consecutively across the 5th and 6th, with the rest the following week. That’s your early May sorted.

This isn’t just for fans of hospital shows, either. If you’re into dramas that ask bigger questions about who gets held accountable—and what happens in those quiet moments when nobody’s looking—you’ll want to block your calendar. Season two of Malpractice looks like it’s set to pull no punches when it comes to the messiness, responsibility, and consequences that swirl around every medical mistake.